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Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation

Brain microenvironment plays an important role in neurodevelopment and pathology, where the extracellular matrix (ECM) and soluble factors modulate multiple cellular processes. Neural cell culture typically relies on heterologous matrices poorly resembling brain ECM. Here, we employed neurospheroids...

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Detalles Bibliográficos
Autores principales: Simão, Daniel, Silva, Marta M., Terrasso, Ana P., Arez, Francisca, Sousa, Marcos F.Q., Mehrjardi, Narges Z., Šarić, Tomo, Gomes-Alves, Patrícia, Raimundo, Nuno, Alves, Paula M., Brito, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094163/
https://www.ncbi.nlm.nih.gov/pubmed/30057262
http://dx.doi.org/10.1016/j.stemcr.2018.06.020