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Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation
Brain microenvironment plays an important role in neurodevelopment and pathology, where the extracellular matrix (ECM) and soluble factors modulate multiple cellular processes. Neural cell culture typically relies on heterologous matrices poorly resembling brain ECM. Here, we employed neurospheroids...
Autores principales: | Simão, Daniel, Silva, Marta M., Terrasso, Ana P., Arez, Francisca, Sousa, Marcos F.Q., Mehrjardi, Narges Z., Šarić, Tomo, Gomes-Alves, Patrícia, Raimundo, Nuno, Alves, Paula M., Brito, Catarina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094163/ https://www.ncbi.nlm.nih.gov/pubmed/30057262 http://dx.doi.org/10.1016/j.stemcr.2018.06.020 |
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