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Prostaglandin E2 Secreted by Thyroid Cancer Cells Contributes to Immune Escape Through the Suppression of Natural Killer (NK) Cell Cytotoxicity and NK Cell Differentiation

Natural killer (NK) cells play important roles in immune surveillance. However, the tumor microenvironment suppresses NK cell function and allows cancer cells to evade immune detection. In this study, we investigated whether the thyroid cancer cell microenvironment has this effect on NK cells. We fo...

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Detalles Bibliográficos
Autores principales: Park, Arum, Lee, Yunhee, Kim, Mi Sun, Kang, Young Ju, Park, Young-Jun, Jung, Haiyoung, Kim, Tae-Don, Lee, Hee Gu, Choi, Inpyo, Yoon, Suk Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094168/
https://www.ncbi.nlm.nih.gov/pubmed/30140269
http://dx.doi.org/10.3389/fimmu.2018.01859