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Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans

Sphingolipids are bio-active metabolites that show structural diversity among eukaryotes. They are essential for growth of all eukaryotic cells but when produced in an uncontrolled manner can lead to cell death and pathologies including auto-immune reactions, cancer, diabetes and neurodegeneration....

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Detalles Bibliográficos
Autores principales: Hannich, J. Thomas, Mellal, Denia, Feng, Suihan, Zumbuehl, Andreas, Riezman, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094178/
https://www.ncbi.nlm.nih.gov/pubmed/30155209
http://dx.doi.org/10.1039/c6sc04831e