Cargando…

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

Protein tyrosine sulfation is a post-translational modification best known for regulating extracellular protein–protein interactions. Tyrosine sulfation is catalysed by two Golgi-resident enzymes termed tyrosylprotein sulfotransferases (TPSTs) 1 and 2, which transfer sulfate from the cofactor PAPS (...

Descripción completa

Detalles Bibliográficos
Autores principales: Byrne, Dominic P., Li, Yong, Ngamlert, Pawin, Ramakrishnan, Krithika, Eyers, Claire E., Wells, Carrow, Drewry, David H., Zuercher, William J., Berry, Neil G., Fernig, David G., Eyers, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094398/
https://www.ncbi.nlm.nih.gov/pubmed/29934490
http://dx.doi.org/10.1042/BCJ20180266