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New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors
Protein tyrosine sulfation is a post-translational modification best known for regulating extracellular protein–protein interactions. Tyrosine sulfation is catalysed by two Golgi-resident enzymes termed tyrosylprotein sulfotransferases (TPSTs) 1 and 2, which transfer sulfate from the cofactor PAPS (...
Autores principales: | Byrne, Dominic P., Li, Yong, Ngamlert, Pawin, Ramakrishnan, Krithika, Eyers, Claire E., Wells, Carrow, Drewry, David H., Zuercher, William J., Berry, Neil G., Fernig, David G., Eyers, Patrick A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094398/ https://www.ncbi.nlm.nih.gov/pubmed/29934490 http://dx.doi.org/10.1042/BCJ20180266 |
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