New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

Sulfation of carbohydrate residues occurs on a variety of glycans destined for secretion, and this modification is essential for efficient matrix-based signal transduction. Heparan sulfate (HS) glycosaminoglycans control physiological functions ranging from blood coagulation to cell proliferation. H...

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Detalles Bibliográficos
Autores principales: Byrne, Dominic P., Li, Yong, Ramakrishnan, Krithika, Barsukov, Igor L., Yates, Edwin A., Eyers, Claire E., Papy-Garcia, Dulcé, Chantepie, Sandrine, Pagadala, Vijayakanth, Liu, Jian, Wells, Carrow, Drewry, David H., Zuercher, William J., Berry, Neil G., Fernig, David G., Eyers, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094399/
https://www.ncbi.nlm.nih.gov/pubmed/29934491
http://dx.doi.org/10.1042/BCJ20180265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094399/
https://www.ncbi.nlm.nih.gov/pubmed/29934491
http://dx.doi.org/10.1042/BCJ20180265

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