Cargando…

New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

Sulfation of carbohydrate residues occurs on a variety of glycans destined for secretion, and this modification is essential for efficient matrix-based signal transduction. Heparan sulfate (HS) glycosaminoglycans control physiological functions ranging from blood coagulation to cell proliferation. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Byrne, Dominic P., Li, Yong, Ramakrishnan, Krithika, Barsukov, Igor L., Yates, Edwin A., Eyers, Claire E., Papy-Garcia, Dulcé, Chantepie, Sandrine, Pagadala, Vijayakanth, Liu, Jian, Wells, Carrow, Drewry, David H., Zuercher, William J., Berry, Neil G., Fernig, David G., Eyers, Patrick A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094399/ https://www.ncbi.nlm.nih.gov/pubmed/29934491 http://dx.doi.org/10.1042/BCJ20180265

Ejemplares similares

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors
por: Byrne, Dominic P., et al.
Publicado: (2018)

Deciphering the substrate recognition mechanisms of the heparan sulfate 3-O-sulfotransferase-3
por: Wander, Rylee, et al.
Publicado: (2021)

Heparan sulfate functions are altered in the osteoarthritic cartilage
por: Shamdani, Sara, et al.
Publicado: (2020)

Increased 3-O-sulfated heparan sulfate in Alzheimer’s disease brain is associated with genetic risk gene HS3ST1
por: Wang, Zhangjie, et al.
Publicado: (2023)

The Emerging Roles of Heparan Sulfate 3-O-Sulfotransferases in Cancer
por: Denys, Agnès, et al.
Publicado: (2019)

Quantitative analysis of heparan sulfate using isotopically labeled calibrants
por: Wang, Zhangjie, et al.
Publicado: (2020)

Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase
por: Thieker, David F., et al.
Publicado: (2018)

The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties
por: Teixeira, Felipe C. O. B., et al.
Publicado: (2020)

Improvement of the stability and catalytic efficiency of heparan sulfate N-sulfotransferase for preparing N-sulfated heparosan
por: Xi, Xintong, et al.
Publicado: (2023)

Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase
por: Kamimura, Keisuke, et al.
Publicado: (2004)

Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer
por: HATABE, SHIGERU, et al.
Publicado: (2013)

Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors
por: Kershaw, Neil M., et al.
Publicado: (2019)

Author Correction: Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase
por: Thieker, David F., et al.
Publicado: (2020)

Anion binding to a cationic europium(iii) probe enables the first real-time assay of heparan sulfotransferase activity
por: Wheeler, Simon, et al.
Publicado: (2021)

Involvement of heparan sulfate 3‐O‐sulfotransferase isoform‐1 in the insulin secretion pathway
por: Takahashi, Iwao, et al.
Publicado: (2012)

3-O-sulfated heparan sulfate interactors target synaptic adhesion molecules from neonatal mouse brain and inhibit neural activity and synaptogenesis in vitro
por: Maïza, Auriane, et al.
Publicado: (2020)

Heparan sulfates and heparan sulfate binding proteins in sepsis
por: Liao, Yi-En, et al.
Publicado: (2023)

A heparan sulfate-based matrix therapy reduces brain damage and enhances functional recovery following stroke
por: Khelif, Yacine, et al.
Publicado: (2018)

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars
por: Uniewicz, Katarzyna A., et al.
Publicado: (2014)

Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression
por: Nagarajan, Arvindhan, et al.
Publicado: (2018)

Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists
por: Zhang, Xing, et al.
Publicado: (2017)

Loss of the Heparan Sulfate Sulfotransferase, Ndst1, in Mammary Epithelial Cells Selectively Blocks Lobuloalveolar Development in Mice
por: Crawford, Brett E., et al.
Publicado: (2010)

Zebrafish 3-O-Sulfotransferase-4 Generated Heparan Sulfate Mediates HSV-1 Entry and Spread
por: Antoine, Thessicar E., et al.
Publicado: (2014)

The heparan sulfate 3-O-sulfotransferases (HS3ST) 2, 3B and 4 enhance proliferation and survival in breast cancer MDA-MB-231 cells
por: Hellec, Charles, et al.
Publicado: (2018)

Cytokines and growth factors cross-link heparan sulfate
por: Migliorini, Elisa, et al.
Publicado: (2015)

Using heparan sulfate octadecasaccharide (18-mer) as a multi-target agent to protect against sepsis
por: Liao, Yi-En, et al.
Publicado: (2023)

Role of Heparan Sulfate 2-O-Sulfotransferase in Prostate Cancer Cell Proliferation, Invasion, and Growth Factor Signaling
por: Ferguson, Brent W., et al.
Publicado: (2011)

Epigenetic Inactivation of Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 2 in Lung Cancer and Its Role in Tumorigenesis
por: Hwang, Jung-Ah, et al.
Publicado: (2013)

Heparan Sulfate and Sialic Acid in Viral Attachment: Two Sides of the Same Coin?
por: Ramos-Martínez, Ivan Emmanuel, et al.
Publicado: (2022)

2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline
por: Chan, Wai Kit, et al.
Publicado: (2015)

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development
por: Kinnunen, Tarja K.
Publicado: (2014)

Correction: Epigenetic Inactivation of Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 2 in Lung Cancer and Its Role in Tumorigenesis
Publicado: (2014)

Introduction to the Molecules Special Edition Entitled ‘Heparan Sulfate and Heparin: Challenges and Controversies’: Some Outstanding Questions in Heparan Sulfate and Heparin Research
por: Yates, Edwin A, et al.
Publicado: (2019)

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
por: Missaghian, Parisa, et al.
Publicado: (2022)

Heparan sulfate gets specific
por: Dove, Alan W.
Publicado: (2001)

Heparan sulfate proteoglycans and cancer
por: Blackhall, F H, et al.
Publicado: (2001)

Heparan Sulfate Proteoglycans in Infection
por: Bartlett, Allison H., et al.
Publicado: (2011)

Heparan Sulfate Proteoglycans in Tauopathy
por: Zhu, Yanan, et al.
Publicado: (2022)

Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3-O-Sulfotransferase 1()
por: Sankaranarayanan, Nehru Viji, et al.
Publicado: (2020)

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota
por: Luis, Ana S, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9c9968snm42a939oqt9g0ntdkf