Novel and Efficient Method for Solid Phase Synthesis of Urea-Containing Peptides Targeting Prostate Specific Membrane Antigen (PSMA) in Comparison with Current Methods

The basic chemical structure of most prostate specific membrane antigen (PSMA) inhibitors which are now in pre-clinical and clinical studies is Glu-Ureido-based peptides. Synthesis of urea-based PSMA inhibitors includes two steps: 1- isocyanate intermediate formation and 2- urea bond formation. In c...

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Detalles Bibliográficos
Autores principales: Mosayebnia, Mona, Rezaeianpour, Sedigheh, Rikhtechi, Pedram, Hajimahdi, Zahra, Beiki, Davood, Kobarfard, Farzad, sabzevari, Omid, Amini, Mohsen, Abdi, Khosrou, Shahhosseini, Soraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094430/
https://www.ncbi.nlm.nih.gov/pubmed/30127815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094430/
https://www.ncbi.nlm.nih.gov/pubmed/30127815

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