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Hypoxia promotes acquisition of aggressive phenotypes in human malignant mesothelioma

BACKGROUND: Hypoxia is a hallmark of the solid tumor microenvironment and is associated with poor outcomes in cancer patients. The present study was performed to investigate mechanisms underlying the hypoxia-induced phenotypic changes using human malignant mesothelioma (HMM) cells. METHODS: Hypoxic...

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Detalles Bibliográficos
Autores principales: Kim, Myung-Chul, Hwang, Sung-Hyun, Kim, Na-Yon, Lee, Hong-Seok, Ji, Sumin, Yang, Yeseul, Kim, Yongbaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094475/
https://www.ncbi.nlm.nih.gov/pubmed/30111297
http://dx.doi.org/10.1186/s12885-018-4720-z