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Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes

BACKGROUND: Colorectal cancer (CRC) remains a leading cause of death worldwide. Utilizing cisplatin in CRC is correlated with severe adverse effects and drug-resistance. Combined anticancer drug-treatment, along with, their enhanced delivery, can effectively kill cancer through multiple pathways. Na...

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Detalles Bibliográficos
Autores principales: Saber, Mona M., Al-mahallawi, Abdulaziz M., Nassar, Noha N., Stork, Björn, Shouman, Samia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094476/
https://www.ncbi.nlm.nih.gov/pubmed/30111296
http://dx.doi.org/10.1186/s12885-018-4727-5