HJURP promotes hepatocellular carcinoma proliferation by destabilizing p21 via the MAPK/ERK1/2 and AKT/GSK3β signaling pathways

BACKGROUND: Holliday junction recognition protein (HJURP) has been implicated in many cancers including hepatocellular carcinoma (HCC). However, the underlying mechanism by which HJURP promotes HCC cell proliferation remains unclear. METHODS: RT-qPCR and immunohistochemistry were used to detect HJUR...

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Detalles Bibliográficos
Autores principales: Chen, Tianchi, Huang, Hechen, Zhou, Yuan, Geng, Lei, Shen, Tian, Yin, Shengyong, Zhou, Lin, Zheng, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094877/
https://www.ncbi.nlm.nih.gov/pubmed/30111352
http://dx.doi.org/10.1186/s13046-018-0866-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094877/
https://www.ncbi.nlm.nih.gov/pubmed/30111352
http://dx.doi.org/10.1186/s13046-018-0866-4

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