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HJURP promotes hepatocellular carcinoma proliferation by destabilizing p21 via the MAPK/ERK1/2 and AKT/GSK3β signaling pathways

BACKGROUND: Holliday junction recognition protein (HJURP) has been implicated in many cancers including hepatocellular carcinoma (HCC). However, the underlying mechanism by which HJURP promotes HCC cell proliferation remains unclear. METHODS: RT-qPCR and immunohistochemistry were used to detect HJUR...

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Detalles Bibliográficos
Autores principales:	Chen, Tianchi, Huang, Hechen, Zhou, Yuan, Geng, Lei, Shen, Tian, Yin, Shengyong, Zhou, Lin, Zheng, Shusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094877/ https://www.ncbi.nlm.nih.gov/pubmed/30111352 http://dx.doi.org/10.1186/s13046-018-0866-4

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