Development of a quadruple qRT-PCR assay for simultaneous identification of highly and low pathogenic H7N9 avian influenza viruses and characterization against oseltamivir resistance

BACKGROUND: During the fifth wave of human H7N9 infections, a novel highly pathogenic (HP) H7N9 variant emerged with an insertion of multiple basic amino acids in the HA cleavage site. Moreover, a neuraminidase inhibitor (NAI) resistance (R292K in NA) mutation was found in H7N9 isolates from humans,...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Li, Shanqin, Wong, Gary, Ma, Sufang, Xu, Zhixiang, Zhao, Xiaonan, Li, Hong, Xu, Wen, Zheng, Haixia, Lin, Jingyan, Zhao, Qi, Liu, Wenjun, Liu, Yingxia, Gao, George F., Bi, Yuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094886/
https://www.ncbi.nlm.nih.gov/pubmed/30111290
http://dx.doi.org/10.1186/s12879-018-3302-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094886/
https://www.ncbi.nlm.nih.gov/pubmed/30111290
http://dx.doi.org/10.1186/s12879-018-3302-7

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