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Development of a quadruple qRT-PCR assay for simultaneous identification of highly and low pathogenic H7N9 avian influenza viruses and characterization against oseltamivir resistance
BACKGROUND: During the fifth wave of human H7N9 infections, a novel highly pathogenic (HP) H7N9 variant emerged with an insertion of multiple basic amino acids in the HA cleavage site. Moreover, a neuraminidase inhibitor (NAI) resistance (R292K in NA) mutation was found in H7N9 isolates from humans,...
Autores principales: | Yang, Yang, Li, Shanqin, Wong, Gary, Ma, Sufang, Xu, Zhixiang, Zhao, Xiaonan, Li, Hong, Xu, Wen, Zheng, Haixia, Lin, Jingyan, Zhao, Qi, Liu, Wenjun, Liu, Yingxia, Gao, George F., Bi, Yuhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094886/ https://www.ncbi.nlm.nih.gov/pubmed/30111290 http://dx.doi.org/10.1186/s12879-018-3302-7 |
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