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The Dipeptide Pro-Gly Promotes IGF-1 Expression and Secretion in HepG2 and Female Mice via PepT1-JAK2/STAT5 Pathway

It has been shown that IGF-1 secretion is influenced by dietary protein or amino acid. However, whether the dipeptides elicit regulatory effects on IGF-1 secretion remains largely unclear. Thus, this study aimed to investigate the effects of the dipeptide Pro-Gly on IGF-1 expression and secretion in...

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Detalles Bibliográficos
Autores principales: Zhang, Mengyuan, Xu, Jingren, Wang, Tao, Wan, Xiaojuan, Zhang, Fenglin, Wang, Lina, Zhu, Xiaotong, Gao, Ping, Shu, Gang, Jiang, Qingyan, Wang, Songbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094964/
https://www.ncbi.nlm.nih.gov/pubmed/30140255
http://dx.doi.org/10.3389/fendo.2018.00424