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Overexpression of Mechano-Growth Factor Modulates Inflammatory Cytokine Expression and Macrophage Resolution in Skeletal Muscle Injury

In muscle regeneration, infiltrating myeloid cells, such as macrophages mediate muscle inflammation by releasing key soluble factors. One such factor, insulin-like growth factor 1 (IGF-1), suppresses inflammatory cytokine expression and mediates macrophage polarization to anti-inflammatory phenotype...

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Detalles Bibliográficos
Autores principales: Sun, Keng-Ting, Cheung, Kwok-Kuen, Au, Shannon W. N., Yeung, Simon S., Yeung, Ella W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094977/
https://www.ncbi.nlm.nih.gov/pubmed/30140235
http://dx.doi.org/10.3389/fphys.2018.00999