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Overexpression of Mechano-Growth Factor Modulates Inflammatory Cytokine Expression and Macrophage Resolution in Skeletal Muscle Injury
In muscle regeneration, infiltrating myeloid cells, such as macrophages mediate muscle inflammation by releasing key soluble factors. One such factor, insulin-like growth factor 1 (IGF-1), suppresses inflammatory cytokine expression and mediates macrophage polarization to anti-inflammatory phenotype...
Autores principales: | Sun, Keng-Ting, Cheung, Kwok-Kuen, Au, Shannon W. N., Yeung, Simon S., Yeung, Ella W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094977/ https://www.ncbi.nlm.nih.gov/pubmed/30140235 http://dx.doi.org/10.3389/fphys.2018.00999 |
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