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Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms

The prevalence of depressive disorders is growing worldwide, notably due to stagnation in the development of drugs with greater antidepressant efficacy, the continuous large proportion of patients who do not respond to conventional antidepressants, and the increasing rate of chronic medical conditio...

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Detalles Bibliográficos
Autores principales: Vancassel, Sylvie, Capuron, Lucile, Castanon, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095005/
https://www.ncbi.nlm.nih.gov/pubmed/30140200
http://dx.doi.org/10.3389/fnins.2018.00499