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Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome

Down syndrome (DS), the main genetic cause of intellectual disability, is associated with an imbalance of excitatory/inhibitory neurotransmitter systems. The phenotypic assessment and pharmacotherapy interventions in DS murine models strongly pointed out glutamatergic neurotransmission alterations (...

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Detalles Bibliográficos
Autores principales: Gómez de Salazar, Macarena, Grau, Cristina, Ciruela, Francisco, Altafaj, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095006/
https://www.ncbi.nlm.nih.gov/pubmed/30140203
http://dx.doi.org/10.3389/fnmol.2018.00226