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SLC26A9 Gene Is Associated With Lung Function Response to Ivacaftor in Patients With Cystic Fibrosis

Ivacaftor is a drug used to treat cystic fibrosis (CF) patients carrying specific gating CFTR mutations. Interpatient variability in the lung response has been shown to be partly explained by rs7512462 in the Solute Carrier Family 26 Member 9 (SLC26A9) gene. In an independent and larger cohort, we a...

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Detalles Bibliográficos
Autores principales: Corvol, Harriet, Mésinèle, Julie, Douksieh, Isman-Hassan, Strug, Lisa J., Boëlle, Pierre-Yves, Guillot, Loïc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095007/
https://www.ncbi.nlm.nih.gov/pubmed/30140228
http://dx.doi.org/10.3389/fphar.2018.00828