Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline

Multiple aspects of molecular regulation, including genetics, epigenetics, and mRNA collectively influence the development of age-related neurologic diseases. Therefore, with the ultimate goal of understanding molecular systems associated with cognitive decline, we infer directed interactions among...

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Detalles Bibliográficos
Autores principales: Tasaki, Shinya, Gaiteri, Chris, Mostafavi, Sara, Yu, Lei, Wang, Yanling, De Jager, Philip L., Bennett, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095043/
https://www.ncbi.nlm.nih.gov/pubmed/30140277
http://dx.doi.org/10.3389/fgene.2018.00294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095043/
https://www.ncbi.nlm.nih.gov/pubmed/30140277
http://dx.doi.org/10.3389/fgene.2018.00294

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