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Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline
Multiple aspects of molecular regulation, including genetics, epigenetics, and mRNA collectively influence the development of age-related neurologic diseases. Therefore, with the ultimate goal of understanding molecular systems associated with cognitive decline, we infer directed interactions among...
Autores principales: | Tasaki, Shinya, Gaiteri, Chris, Mostafavi, Sara, Yu, Lei, Wang, Yanling, De Jager, Philip L., Bennett, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095043/ https://www.ncbi.nlm.nih.gov/pubmed/30140277 http://dx.doi.org/10.3389/fgene.2018.00294 |
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