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Design of a Small-Scale Multi-Inlet Vortex Mixer for Scalable Nanoparticle Production and Application to the Encapsulation of Biologics by Inverse Flash NanoPrecipitation
Flash NanoPrecipitation is a scalable approach to generate polymeric nanoparticles using rapid micromixing in specially designed geometries such as a confined impinging jets mixer or a Multi-Inlet Vortex Mixer (MIVM). A major limitation of formulation screening using the MIVM is that a single run re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095068/ https://www.ncbi.nlm.nih.gov/pubmed/29772223 http://dx.doi.org/10.1016/j.xphs.2018.05.003 |