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Matrix metalloproteinase 2/9-triggered-release micelles for inhaled drug delivery to treat lung cancer: preparation and in vitro/in vivo studies
BACKGROUND: Improvement in drug accumulation in the lungs through inhalation administration and high expression of MMP2 and MMP9 in lung tumors have both been widely reported. METHODS: MMP2/9-triggered-release micelles were constructed and in vitro and in vivo studies of inhalation administration ag...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095127/ https://www.ncbi.nlm.nih.gov/pubmed/30147314 http://dx.doi.org/10.2147/IJN.S166584 |