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Strong correlation of lumefantrine concentrations in capillary and venous plasma from malaria patients

BACKGROUND: Lumefantrine is a long-acting antimalarial drug with an elimination half-life of over 3 days and protein binding of 99 percent. Correlation of lumefantrine concentrations from capillary plasma via fingerprick (C(c)) versus venous plasma (C(v)) remains to be defined. METHODS: Venous and c...

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Detalles Bibliográficos
Autores principales: Huang, Liusheng, Mwebaza, Norah, Kajubi, Richard, Marzan, Florence, Forsman, Camilla, Parikh, Sunil, Aweeka, Francesca T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095545/
https://www.ncbi.nlm.nih.gov/pubmed/30114201
http://dx.doi.org/10.1371/journal.pone.0202082