Identifying feasible operating regimes for early T-cell recognition: The speed, energy, accuracy trade-off in kinetic proofreading and adaptive sorting

In the immune system, T cells can quickly discriminate between foreign and self ligands with high accuracy. There is evidence that T-cells achieve this remarkable performance utilizing a network architecture based on a generalization of kinetic proofreading (KPR). KPR-based mechanisms actively consu...

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Detalles Bibliográficos
Autores principales: Cui, Wenping, Mehta, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095552/
https://www.ncbi.nlm.nih.gov/pubmed/30114236
http://dx.doi.org/10.1371/journal.pone.0202331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095552/
https://www.ncbi.nlm.nih.gov/pubmed/30114236
http://dx.doi.org/10.1371/journal.pone.0202331

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