Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast

Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms remain unknown. Using various orthogonal single-cell approaches, we show that cell size increases linearly with centromere (CEN) copy number in budding yeast. This effect is due to a G1 delay mediated by incre...

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Detalles Bibliográficos
Autores principales: Martínez-Láinez, Joan M., Moreno, David F., Parisi, Eva, Clotet, Josep, Aldea, Martí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095599/
https://www.ncbi.nlm.nih.gov/pubmed/30080861
http://dx.doi.org/10.1371/journal.pbio.2005388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095599/
https://www.ncbi.nlm.nih.gov/pubmed/30080861
http://dx.doi.org/10.1371/journal.pbio.2005388

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