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Chronic neuropathic pain reduces opioid receptor availability with associated anhedonia in rat

The opioid system plays a critical role in both the experience and management of pain. Although acute activation of the opioid system can lead to pain relief, the effects of chronic pain on the opioid system remain opaque. Cross-sectional positron emission tomography (PET) studies show reduced avail...

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Detalles Bibliográficos
Autores principales: Thompson, Scott J., Pitcher, Mark H., Stone, Laura S., Tarum, Farid, Niu, Gang, Chen, Xiaoyuan, Kiesewetter, Dale O., Schweinhardt, Petra, Bushnell, M. Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095806/
https://www.ncbi.nlm.nih.gov/pubmed/29794614
http://dx.doi.org/10.1097/j.pain.0000000000001282