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Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1)

Expression of a constitutively active Rho A (V14Rho) in podocytes in vivo induces albuminuria and foot process (FP) effacement. These effects may be mediated by the Rho A effector Rho kinase (ROK); but inhibition of ROK with Y27632 failed to attenuate albuminuria or FP effacement in V14Rho mice. ROK...

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Detalles Bibliográficos
Autores principales: Wang, Liming, Buckley, Anne F., Spurney, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095849/
https://www.ncbi.nlm.nih.gov/pubmed/30115939
http://dx.doi.org/10.1038/s41598-018-30115-3