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Effect of valproate and pregabalin on human anxiety-like behaviour in a randomised controlled trial

Valproate is an anticonvulsant drug with strong preclinical evidence for reducing anxiety behaviour in rodents but no clear clinical evidence. To motivate clinical trials, we here investigate the use of valproate in a translational human model of anxiety behaviour. In a double-blind, randomised, pla...

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Detalles Bibliográficos
Autores principales: Bach, Dominik R., Korn, Christoph W., Vunder, Johanna, Bantel, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095858/
https://www.ncbi.nlm.nih.gov/pubmed/30115911
http://dx.doi.org/10.1038/s41398-018-0206-7