Biased genome editing using the local accumulation of DSB repair molecules system

Selective genome editing such as gene knock-in has recently been achieved by administration of chemical enhancer or inhibitor of particular DNA double-strand break (DSB) repair pathways, as well as overexpression of pathway-specific genes. In this study, we attempt to enhance the efficiency further...

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Detalles Bibliográficos
Autores principales: Nakade, Shota, Mochida, Keiji, Kunii, Atsushi, Nakamae, Kazuki, Aida, Tomomi, Tanaka, Kohichi, Sakamoto, Naoaki, Sakuma, Tetsushi, Yamamoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095859/
https://www.ncbi.nlm.nih.gov/pubmed/30115916
http://dx.doi.org/10.1038/s41467-018-05773-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095859/
https://www.ncbi.nlm.nih.gov/pubmed/30115916
http://dx.doi.org/10.1038/s41467-018-05773-6

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