Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model

The dopaminergic hypothesis of schizophrenia (SZ) postulates that dopaminergic over activity causes psychosis, a central feature of SZ, based on the observation that blocking dopamine (DA) improves psychotic symptoms. DA is known to have both receptor- and non-receptor-mediated effects, including ox...

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Detalles Bibliográficos
Autores principales: Duan, Jubao, Göring, Harald H. H., Sanders, Alan R., Moy, Winton, Freda, Jessica, Drigalenko, Eugene I., Kos, Mark, He, Deli, Gejman, Pablo V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095865/
https://www.ncbi.nlm.nih.gov/pubmed/30115913
http://dx.doi.org/10.1038/s41398-018-0216-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095865/
https://www.ncbi.nlm.nih.gov/pubmed/30115913
http://dx.doi.org/10.1038/s41398-018-0216-5

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