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Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model
The dopaminergic hypothesis of schizophrenia (SZ) postulates that dopaminergic over activity causes psychosis, a central feature of SZ, based on the observation that blocking dopamine (DA) improves psychotic symptoms. DA is known to have both receptor- and non-receptor-mediated effects, including ox...
Autores principales: | Duan, Jubao, Göring, Harald H. H., Sanders, Alan R., Moy, Winton, Freda, Jessica, Drigalenko, Eugene I., Kos, Mark, He, Deli, Gejman, Pablo V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095865/ https://www.ncbi.nlm.nih.gov/pubmed/30115913 http://dx.doi.org/10.1038/s41398-018-0216-5 |
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