The polymorphism rs35767 at IGF1 locus is associated with serum urate levels

Previous studies suggested that the IGF-1/IGF-1 receptor signaling pathway may contribute to regulate uric acid levels. To confirm this hypothesis, we assessed the effects of the IGF-1-raising genetic variant rs35767 on urate levels in serum and urine, and we investigated IGF-1 ability to modulate t...

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Detalles Bibliográficos
Autores principales: Mannino, Gaia C., Fuoco, Anastasia, Marini, Maria A., Spiga, Rosangela, Di Fatta, Concetta, Mancuso, Elettra, Perticone, Francesco, Andreozzi, Francesco, Sesti, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095867/
https://www.ncbi.nlm.nih.gov/pubmed/30115944
http://dx.doi.org/10.1038/s41598-018-29665-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095867/
https://www.ncbi.nlm.nih.gov/pubmed/30115944
http://dx.doi.org/10.1038/s41598-018-29665-3

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