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The polymorphism rs35767 at IGF1 locus is associated with serum urate levels

Previous studies suggested that the IGF-1/IGF-1 receptor signaling pathway may contribute to regulate uric acid levels. To confirm this hypothesis, we assessed the effects of the IGF-1-raising genetic variant rs35767 on urate levels in serum and urine, and we investigated IGF-1 ability to modulate t...

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Detalles Bibliográficos
Autores principales:	Mannino, Gaia C., Fuoco, Anastasia, Marini, Maria A., Spiga, Rosangela, Di Fatta, Concetta, Mancuso, Elettra, Perticone, Francesco, Andreozzi, Francesco, Sesti, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095867/ https://www.ncbi.nlm.nih.gov/pubmed/30115944 http://dx.doi.org/10.1038/s41598-018-29665-3

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