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An essential role for the nuclear protein Akirin2 in mouse limb interdigital tissue regression

The regulation of interdigital tissue regression requires the interplay of multiple spatiotemporally-controlled morphogen gradients to ensure proper limb formation and release of individual digits. Disruption to this process can lead to a number of limb abnormalities, including syndactyly. Akirins a...

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Detalles Bibliográficos
Autores principales: Bosch, Peter J., Fuller, Leah C., Weiner, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095873/
https://www.ncbi.nlm.nih.gov/pubmed/30116001
http://dx.doi.org/10.1038/s41598-018-30801-2