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Discovery of cationic nonribosomal peptides as Gram-negative antibiotics through global genome mining
The worldwide prevalence of infections caused by antibiotic-resistant Gram-negative bacteria poses a serious threat to public health due to the limited therapeutic alternatives. Cationic peptides represent a large family of antibiotics and have attracted interest due to their diverse chemical struct...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095874/ https://www.ncbi.nlm.nih.gov/pubmed/30115920 http://dx.doi.org/10.1038/s41467-018-05781-6 |