Reporter PET Images Bortezomib Treatment-Mediated Suppression of Cancer Cell Proteasome Activity

Proteasomal protein degradation is a promising target for cancer therapy. Here, we developed a positron emission tomography (PET) technique based on the sodium-iodide symporter (NIS) gene fused with the carboxyl-terminal of ornithine decarboxylase (cODC) that noninvasively images cancer cells with i...

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Detalles Bibliográficos
Autores principales: Lee, Jin Hee, Jung, Kyung-Ho, Quach, Cung Hoa Thien, Park, Jin Won, Moon, Seung Hwan, Cho, Young Seok, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095884/
https://www.ncbi.nlm.nih.gov/pubmed/30116045
http://dx.doi.org/10.1038/s41598-018-29642-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095884/
https://www.ncbi.nlm.nih.gov/pubmed/30116045
http://dx.doi.org/10.1038/s41598-018-29642-w

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