Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

Glycosaminoglycans (GAGs) bind a large array of proteins and mediate fundamental and diverse roles in human physiology. Ion pair interactions between protein lysines/arginines and GAG sulfates/carboxylates mediate binding. Neutrophil-activating chemokines (NAC) are GAG-binding proteins, and their se...

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph, Prem Raj B., Sawant, Kirti V., Iwahara, Junji, Garofalo, Roberto P., Desai, Umesh R., Rajarathnam, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095893/
https://www.ncbi.nlm.nih.gov/pubmed/30115951
http://dx.doi.org/10.1038/s41598-018-30697-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095893/
https://www.ncbi.nlm.nih.gov/pubmed/30115951
http://dx.doi.org/10.1038/s41598-018-30697-y

Ejemplares similares