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Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

Glycosaminoglycans (GAGs) bind a large array of proteins and mediate fundamental and diverse roles in human physiology. Ion pair interactions between protein lysines/arginines and GAG sulfates/carboxylates mediate binding. Neutrophil-activating chemokines (NAC) are GAG-binding proteins, and their se...

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Detalles Bibliográficos
Autores principales:	Joseph, Prem Raj B., Sawant, Kirti V., Iwahara, Junji, Garofalo, Roberto P., Desai, Umesh R., Rajarathnam, Krishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095893/ https://www.ncbi.nlm.nih.gov/pubmed/30115951 http://dx.doi.org/10.1038/s41598-018-30697-y

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