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Size control in mammalian cells involves modulation of both growth rate and cell cycle duration

Despite decades of research, how mammalian cell size is controlled remains unclear because of the difficulty of directly measuring growth at the single-cell level. Here we report direct measurements of single-cell volumes over entire cell cycles on various mammalian cell lines and primary human cell...

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Detalles Bibliográficos
Autores principales: Cadart, Clotilde, Monnier, Sylvain, Grilli, Jacopo, Sáez, Pablo J., Srivastava, Nishit, Attia, Rafaele, Terriac, Emmanuel, Baum, Buzz, Cosentino-Lagomarsino, Marco, Piel, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095894/
https://www.ncbi.nlm.nih.gov/pubmed/30115907
http://dx.doi.org/10.1038/s41467-018-05393-0