Insight into the molecular mechanism behind PEG-mediated stabilization of biofluid lipases

Bioconjugates established between anionic polyethylene glycol (PEG) based polymers and cationic proteins have proven to be a promising strategy to engineer thermostable biocatalysts. However, the enzyme activity of these bioconjugates is very low and the mechanism of non-covalent PEG-stabilization i...

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Detalles Bibliográficos
Autores principales: Pérez, Bianca, Coletta, Andrea, Pedersen, Jannik N., Petersen, Steen V., Periole, Xavier, Pedersen, Jan Skov, Sessions, Richard B., Guo, Zheng, Perriman, Adam, Schiøtt, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095910/
https://www.ncbi.nlm.nih.gov/pubmed/30115948
http://dx.doi.org/10.1038/s41598-018-29871-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095910/
https://www.ncbi.nlm.nih.gov/pubmed/30115948
http://dx.doi.org/10.1038/s41598-018-29871-z

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