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Retrograde Transport by Clathrin-Coated Vesicles is Involved in Intracellular Transport of PrP(Sc) in Persistently Prion-Infected Cells

Intracellular dynamics of an abnormal isoform of prion protein (PrP(Sc)) are tightly associated with prion propagation. However, the machineries involved in the intracellular trafficking of PrP(Sc) are not fully understood. Our previous study suggested that PrP(Sc) in persistently prion-infected cel...

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Detalles Bibliográficos
Autores principales: Yamasaki, Takeshi, Suzuki, Akio, Hasebe, Rie, Horiuchi, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095914/
https://www.ncbi.nlm.nih.gov/pubmed/30115966
http://dx.doi.org/10.1038/s41598-018-30775-1