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Betulinic acid exerts potent antitumor effects on paclitaxel-resistant human lung carcinoma cells (H460) via G2/M phase cell cycle arrest and induction of mitochondrial apoptosis

Betulinic acid is a pentacyclic plant compound obtained from the bark of white birch trees and has been demonstrated to exhibit notable pharmacological properties. In the present study, the anticancer potential of betulinic acid on paclitaxel-resistant lung cancer cell line (H460) was evaluated. Cel...

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Detalles Bibliográficos
Autores principales: Zhan, Xiao-Kai, Li, Jun-Ling, Zhang, Sen, Xing, Pu-Yuan, Xia, Meng-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096078/
https://www.ncbi.nlm.nih.gov/pubmed/30127971
http://dx.doi.org/10.3892/ol.2018.9097