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Betulinic acid exerts potent antitumor effects on paclitaxel-resistant human lung carcinoma cells (H460) via G2/M phase cell cycle arrest and induction of mitochondrial apoptosis
Betulinic acid is a pentacyclic plant compound obtained from the bark of white birch trees and has been demonstrated to exhibit notable pharmacological properties. In the present study, the anticancer potential of betulinic acid on paclitaxel-resistant lung cancer cell line (H460) was evaluated. Cel...
Autores principales: | Zhan, Xiao-Kai, Li, Jun-Ling, Zhang, Sen, Xing, Pu-Yuan, Xia, Meng-Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096078/ https://www.ncbi.nlm.nih.gov/pubmed/30127971 http://dx.doi.org/10.3892/ol.2018.9097 |
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