Cargando…

Doxorubicin combined with Notch1-targeting siRNA for the treatment of gastric cancer

Notch1, a transmembrane receptor that has a notable role in gastric cancer (GC) as an oncogene, has been reported to be involved in doxorubicin resistance. Thus, Notch1 is a potential therapeutic target for GC. In the present study, the protein levels of Notch1 intracellular domain (NICD; a marker o...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Wei, Tan, Wei, Huang, Xu, Yu, Hong Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096196/
https://www.ncbi.nlm.nih.gov/pubmed/30127866
http://dx.doi.org/10.3892/ol.2018.9039