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Epstein-Barr virus-encoded microRNA BART7 downregulates major histocompatibility complex class I chain-related peptide A and reduces the cytotoxicity of natural killer cells to nasopharyngeal carcinoma

Evasion from natural killer (NK) cell surveillance enables cancer to proliferate and spread at the early stages. NK cells mediate specific cytolysis by activation of the triggering receptors on their cell surface, of which the communication between natural killer group 2, member D (NKG2D) and major...

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Detalles Bibliográficos
Autores principales: Wong, Thian-Sze, Chen, Siqi, Zhang, Min-Juan, Chan, Jimmy Yu-Wai, Gao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096257/
https://www.ncbi.nlm.nih.gov/pubmed/30127876
http://dx.doi.org/10.3892/ol.2018.9041