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Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase

N-acetylphosphoglucosamine mutase (AGM1) is a key component of the hexosamine biosynthetic pathway that produces UDP-GlcNAc, an essential precursor for a wide range of glycans in eukaryotes. AGM belongs to the α-d-phosphohexomutase metalloenzyme superfamily and catalyzes the interconversion of N-ace...

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Detalles Bibliográficos
Autores principales: Raimi, Olawale G., Hurtado-Guerrero, Ramon, vanAalten, Daan M.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096347/
https://www.ncbi.nlm.nih.gov/pubmed/29967067
http://dx.doi.org/10.1042/BCJ20180172