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Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase
N-acetylphosphoglucosamine mutase (AGM1) is a key component of the hexosamine biosynthetic pathway that produces UDP-GlcNAc, an essential precursor for a wide range of glycans in eukaryotes. AGM belongs to the α-d-phosphohexomutase metalloenzyme superfamily and catalyzes the interconversion of N-ace...
Autores principales: | Raimi, Olawale G., Hurtado-Guerrero, Ramon, vanAalten, Daan M.F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096347/ https://www.ncbi.nlm.nih.gov/pubmed/29967067 http://dx.doi.org/10.1042/BCJ20180172 |
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